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Neurology International Open (NIO) is an
Open Access journal publishing the very
latest research results and developments
in neurology and neuroscience.

The journal publishes guidelines, original
papers, reviews, and letters to the editors.
As an Open Access publication, all content
is freely available to read online.
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Welcome to Thieme Open

Thieme Open is the gateway to the Open Access journal content from the Thieme Publishing Group.  It covers both fully Open Access journals, as well as articles published on an Open Access basis in our subscription journals. All Open Access content published by Thieme is freely and permanently available online for everyone, increasing the visibility, usage and impact of your work.

As you would expect from Thieme, all our Open Access journals are subject to thorough, independent peer review. Our Open Access articles meet the same high quality of editorial, author and production services you have gotten used to from Thieme.  Check out the latest content below and see for yourself!


Featured Open Access Articles

Isolated Spontaneous Midbrain Hemorrhage in a 14-Year-Old Boy (Journal of Neurological Surgery Reports)

Kim-Long R. Nguyen, Hyunyoung Kim, Laszlo Nagy

Isolated spontaneous midbrain hemorrhages are rare because they are usually secondary to hemorrhages from inferior structures such as the pons and cerebellum, or superior structures such as the thalamus and putamen. While the etiologies are largely unidentified, the most common ones are vascular malformations and bleeding diathesis with hypertension being relatively uncommon.  Read more.

The Fleur-de-PAP Flap for Bilateral Breast Reconstruction (Journal of Reconstructive Microsurgery Open)

Katharine Saussy, Mark W. Stalder, Stephen J. Delatte, Robert J. Allen, Hugo St Hilaire

The authors present the case of a 42-year-old female patient who underwent autologous breast reconstruction using a new perforator flap designed from the medial and posterior thigh. Due to a prior abdominoplasty, the patient's abdominal donor site was unavailable to reconstruct her large, ptotic breasts, so an alternate approach was undertaken. Read more.

Inhibition of Degranulation of RBL-2H3 Cells by Extracts and Compounds from Armillaria ostoyae (Planta Medica International Open)

Simon Merdivan, Kristina Jenett-Siems, Karsten Siems, Timo Niedermeyer, Michael J. Solis, Martin Unterseher, Ulrike Lindequist

Armillaria ostoyae (Romagn.) Herink is an edible honey mushroom from the family Physalacriaceae (Agaricales, Basidiomycota). Dichloromethane extracts of mushroom mycelium and fruiting bodies exhibited a significant degranulation inhibiting effect on RBL-2H3 cells using noncytotoxic concentrations. Read more.

Estrone and Estradiol Levels in Breast Cancer Patients Using Anastrozole Are Not Related to Body Mass Index (RBGO Gynecology and Obstetrics)

Agnaldo Lopes da Silva Filho, Susan Contreras, Jorge Milhem Haddad

Obesity is associated with an increased risk for breast cancer. Recent studies have shown that aromatase inhibitors may be less effective in women with a high body mass index (BMI). The aim of this study was to establish the relationship between the BMI and plasma estrone and estradiol levels in postmenopausal women with hormone receptor-positive breast cancer using anastrozole.  Read more.


A Forefoot Strike Requires the Highest Forces Applied to the Foot Among Foot Strike Patterns (Sports Medicine International Open)

Satoru Hashizume, Toshio Yanagiya

Ground reaction force is often used to predict the potential risk of injuries but may not coincide with the forces applied to commonly injured regions of the foot. This study examined the forces applied to the foot, and the associated moment arms made by three foot strike patterns. Read more.

Latest Open Access Articles