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Neurology International Open (NIO) is an
Open Access journal publishing the very
latest research results and developments
in neurology and neuroscience.

The journal publishes guidelines, original
papers, reviews, and letters to the editors.
As an Open Access publication, all content
is freely available to read online.
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Welcome to Thieme Open

Thieme Open is the gateway to the Open Access journal content from the Thieme Publishing Group.  It covers both fully Open Access journals, as well as articles published on an Open Access basis in our subscription journals. All Open Access content published by Thieme is freely and permanently available online for everyone, increasing the visibility, usage and impact of your work.

As you would expect from Thieme, all our Open Access journals are subject to thorough, independent peer review. Our Open Access articles meet the same high quality of editorial, author and production services you have gotten used to from Thieme.  Check out the latest content below and see for yourself!


Featured Open Access Articles

Spinal Intramedullary Tuberculosis (The Surgery Journal)

Varghese, Prithvi; Abdul Jalal, Muhammed Jasim; Kandathil, Julio Chacko; Mathew, Iona Leekha

Tuberculosis of the central nervous system accounts for approximately 1% of all cases of tuberculosis and 50% of these involve the spine. Intramedullary involvement is rare in tuberculosis. Clinical presentation of spinal intramedullary tuberculosis (SIMT) is similar to intramedullary spinal cord tumor. Here, we report the case of a 49-year-old female with dull aching pain of both upper limbs of 1-week duration.  Read more.

Clinical Applications of Contrast-Enhanced Ultrasound in the Pediatric Work-Up of Focal Liver Lesions and Blunt Abdominal Trauma: A Systematic Review (Ultrasound International Open)

Laugesen, Nicolaj Grønbæk; Nolsoe, Christian Pallson; Rosenberg, Jacob

In pediatrics ultrasound has long been viewed more favorably than imaging that exposes patients to radiation and iodinated contrast or requires sedation. It is child-friendly and diagnostic capabilities have been improved with the advent of contrast-enhanced ultrasound (CEUS). The application of CEUS is indeed promising. However, no ultrasound contrast agent manufactured today is registered for pediatric use in Europe. The contrast agent SonoVue® has recently been approved by the FDA under the name of Lumason® to be used in hepatic investigations in adults and children. This article reviews the literature with respect to 2 specific applications of CEUS in children: 1) identification of parenchymal injuries following blunt abdominal trauma, and 2) classification of focal liver lesions. Read more.

Serial Measurement of Superior Vena Cava Flow in Evaluation of the Clinical Severity of Pial Arteriovenous Fistula in an Infant (American Journal of Perinatology Reports)

Ago, Mako; Masumoto, Kenichi; Uchiyama, Atsushi; Aihara, Yasuo; Okada, Yoshikazu; Kusuda, Satoshi

Pial arteriovenous fistula (AVF) is composed of one or more direct arterial feeding vessels with a single draining vein without nidus. A patient with the disease with high-flow AV shunting in the neonatal period not only suffers from high-output cardiac failure but also shows secondary neurological sequelae. In vein of Galen aneurysmal malformation, superior vena cava (SVC) flow measurements provide useful prognostic information. Read more.

Redefinition of Atypical Parkinsonian Syndromes (Neurology International Open)

Respondek, G.; Levin, J.; Höglinger, G. U.

The definition of atypical parkinsonian syndromes is undergoing a change. The umbrella concept of atypical parkinsonian syndromes includes diseases with different underlying pathologies. These are, on the one hand, multiple system atrophy (MSA) and dementia with Lewy bodies (DLB), both of which are characterized by intracellular aggregates of the protein alpha-synuclein, and on the other hand, corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP), which are characterized by aggregates of the protein tau.  Read more.


Endovascular Treatment for Idiopathic Intracranial Hypertension Improves Clinical Symptoms and Signs (Brazilian Neurosurgery)

Silva, João Miguel Almeida; Conti, Mario Luiz Marques; Aguiar, Guilherme Brasileiro; Jory, Mauricio; Monzillo, Paulo Helio; Veiga, José Carlos Esteves

Ground reaction force is often used to predict the potential risk of injuries but may not coincide with the forces applied to commonly injured regions of the foot. This study examined the forces applied to the foot, and the associated moment arms made by three foot strike patterns. Read more.

Latest Open Access Articles